Gastrointestinals

Genetic variation influences the absorption and efflux of drugs in the intestine, the metabolism of drugs in the liver and the effects of these drugs on their target proteins. Indeed, variations in genes whose products have a role in the pathophysiology of gastrointestinal diseases, have been shown to affect the response of patients to therapy.

Antiemetics

  • Aprepitant (Emend-oral®)
  • Dolasetron (Anzemet®)
  • Dronabinol
  • Fosaprepitant
  • Granisetron
  • Metoclopramide
  • Netupitant-Palonosetron
  • Ondansetron
  • Palonosetron
  • Rolapitant

Proton Pump Inhibitors

  • Dexlansoprazole (Dexilant®)
  • Esomeprazole (Nexium®)
  • Lansoprazole (Prevacid®)
  • Omeprazole (Prilosec®)
  • Pantoprazole (Protonix®)
  • Rabeprazole (Aciphex®)
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