Infections

Important genes conferring resistance to antibiotics can be detected, and this information can be used to choose appropriate antibiotic therapy. The genome of the host may reveal susceptibility genes and new drug targets that may be used in the treatment of infectious diseases. Thus far, polymorphisms in genes of the host immune system have been associated with susceptibility to infections and response to treatment. Pharmacogenomics has the potential to help on prevention, diagnosis, and treatment of infectious diseases.

Antifungals

  • Amphotericin B (AmBisome®)
  • Anidaluafungin (Eraxis ®)
  • Caspofungin (Cancidas ®)
  • Fluconazole (Diflucan®)
  • Isavuconazonium (Cresemba®)
  • Itraconazole (Sporanox®)
  • Micafungin (Myacmine®)
  • Posaconazole (Nozafil®)
  • Voriconazole (Vfend®)

Anti-HIV Agents

  • Dolutegravir (Tivicay®)
  • Raltegravir (Isentress®)

Antimalarial

  • Proguanil (Paludrine®)
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