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Science
The Advanced NGx nutrigenetic test is the result of 16 years of expertise in the field of Nutrigenetic and Nutrigenomic research in one of the most prestigious universities in The United States, The University of North Carolina at Chapel Hill.
At the design and development of the test benefited from a collaboration between Advanced Nutrigenomics and two other prestigious partners, which continue to support the project:
- Duke University, through the DNA Analysis Facility (read more here...) - Thermo Fisher Scientific which owns the sequencing patent for the Ion Torrent platform (read more here...). The sequencing platform for the Advanced NGx test is the Ion PGM Dx system, approved by the Federal Drug Administration, along with the platform's dedicated test reagents (FDA, USA, Class II Medical Device read more here...)
Scientific board
Mihai Niculescu
(MD, PhD)
Founder and CEO Advanced Nutrigenomics, Adjunct Professor at The "Victor Bab...
(Read more)
Founder and CEO Advanced Nutrigenomics, Adjunct Professor at The "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.

Internationally recognized expert in nutrigenomics. Between 2008 and 2015, having his own laboratory at The Nutrition Research Institute (UNC Chapel Hill), Dr. Niculescu focused on the relationship between nutrients (such as choline, fatty acids, polyphenols, etc) and the genetic and epigenetic background, as well as on the impact of nutrition upon epigenetic transgenerational inheritance. In 2015 Dr. Niculescu founded the startup company Advanced Nutrigenomics, serving also as Chief Science Officer for another startup company (Nutrigene Sciences) until 2016. In 2016 he became the project director of the NUTRIGEN project at UMF Timisoara, a 2 M euro grant awarded with EU funds by the Romanian Government.

His current work involves the development of his company in the field of nutrigenetics (Cary, North Carolina), and his work in Timisoara, Romania. He is the author of more than 50 scientific articles, book chapters, and the editor of a book on nutritional epigenetics. He is a peer reviewer for more than 30 scientific journals, and a grant reviewer for NIH (USA), MRC and DIABETES (UK), NWO (The Netherlands), KAUST (Saudi Arabia), and The QATAR Fund (Qatar).

He graduated the Carol Davila School of Medicine, Bucharest, Romania in 1995. He obtained his PhD at The University of North Carolina at Chapel Hill in 2005.
Natalia Cucu
(PhD)
Professor, Department of Genetics, Faculty of Biology, University of Buchare...
(Read more)
Professor, Department of Genetics, Faculty of Biology, University of Bucharest. Chair for the Association for Epigenetics and Metanolomics (AEGM).

Professor Natalia Cucu has more than 20 years of expertise in epigenetics and molecular biology. Her teaching and research activity focuses on the intersection between genetics and epigenetics, and their roles in defining non-invasive early biomarkers and non-invasive diagnostic tools, as well as their use in the personalized treatment of cancer.

She is an active member of the Romanian Society of Medical Genetics (SRGM), and collaborates with geneticists in the field of reproductive malignancies diagnosis and rare diseases using biomarkers. President of the Association of Epigenetics and Metabolomics, implements new revolutionary concepts in biomedicine and nutrition.

After graduating from University of Bucharest (Biochemistry), she was involved in several post-graduate programs, including postdoctoral studies at The University Louisville, Kentucky (U.S.A.), and a doctoral program graduated from University of Bucharest.
Martin Kohlmeier
(MD, PhD)
Research Professor, Department of Nutrition, Nutrition Research Institute, T...
(Read more)
Research Professor, Department of Nutrition, Nutrition Research Institute, The University of North Carolina at Chapel Hill, U.S.A. Visiting Fellow, Wolfson College, Cambridge University, U.K. Secretary, International Society of Nutrigenetics/Nutrigenomics.

Internationally recognized as an expert in nutrigenomics, Dr. Kohlmeier is the author of more than 65 peer reviewed scientific articles, and the author of two standard textbooks: "Nutrient Metabolism" and "Nutrigenetics: The Science of Personal Nutrition". His expertise in nutrigenomics and nutrigenetics is demonstrated by his involvement in peer and grant reviews, numerous editorial activities, his involvement as grant reviewer, and by his lectures at conferences. His long-term interests concern the role of genetic variations in the metabolism of nutrients and the translation of nutrigenetic information into practice.

Dr. Kohlmeier is the Chair of the ASN Nutrition Educators Meeting and Mentoring Committee, and Secretary for the International Society of Nutrigenetics and Nutrigenomics.

After medical school and residency training, Dr. Martin Kohlmeier completed graduate studies in bioinformatics, clinical chemistry and laboratory medicine at Heidelberg University, at the Max Planck Institute for Nutrition Research in Dortmund, and later at the Free University in Berlin.
Dr. Aurelian Bidulescu
(MD, PhD)
Associate Professor, Department of Epidemiology and Biostatistics, Indiana U...
(Read more)
Associate Professor, Department of Epidemiology and Biostatistics, Indiana University, U.S.A. Principal Investigator for one of the Jackson Heart Study "National Vanguard Centers", and Member/Investigator of the AdipoGEN International Consortium.

Dr. Bidulescu is an internationally recognized expert in the epidemiology of cardiovascular disease, and the association between genetic variations and the burden of metabolic diseases. He is the author of more than 45 peer reviewed scientific articles, ad-hoc grant reviewer for The National Institutes of Health (NIH), and for numerous scientific jolurnals.

His research interests include the areas of cardiovascular disease (CVD), metabolic syndrome components (such as abdominal obesity), adipokines (such as adiponectin, leptin and ghrelin), biomarkers for heart failure and left ventricular mass hypertrophy (such as brain natriuretic peptides) and their genetic components (genome wide association studies in the NHLBI CARe, whole exome sequencing in Minority Health GRID consortium), in relationship with ethnic disparities.

Recent interests include sleep quality and related biomarkers (ghrelin), coronary calcium score and bone mineral metabolism markers (FGF23), and psychosocial stress in relationship with obesity and CVD. Dr. Bidulescu initiated a nutritional epidemiology research project that investigates the role of dietary methyl-donors (such as betaine) as putative CVD risk factors.

Following his medical training at Carol Davila University of Medicine, Bucharest, Romania, and his master in Public Health at the Yale University, U.S.A., Dr. Bidulescu obtained his PhD at The University of North Carolina at Chapel Hill, U.S.A.
Emilia Severin
(PhD)
Professor of Genetics, School of Dentistry, "Carol Davila" University of Med...
(Read more)
Professor of Genetics, School of Dentistry, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania. Member of the European Union Committee of Experts in Rare Diseases (EUCERD/CEGRD). Vice-chair for the National Council for Rare Diseases. Member of the Committee for Medical Genetics, Romanian Health Ministry.

Professor Emilia Severin is a recognized expert in rare genetic diseases. Besides her teaching and research activity, she is an internationally recognized expert in health care policies involving genetic and rare genetic diseases. She is actively involved in policy making and the regulatory development in health care, at both national and EU levels. Professor Emilia Severin is actively involved in the formation of human resources in health care and in the management of rare genetic diseases.

After graduating The University of Bucharest (Biology), Professor Emilia Severin obtained a master degree in Systemic Ecology and Environmental Protection, followed by a doctoral degree (PhD) in Genetics from "Carol Davila" University of Medicine and Pharmacy.
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Genetic test configurations
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